Increased frequency of lymphocytic mitotic non-disjunction in recurrent spontaneous aborters.
نویسندگان
چکیده
Hypermodal chromosomal spreads occurred significantly more frequently in lymphocytes from couples with recurrent spontaneous abortion than from comparison populations. Previously, we reported a similarly increased frequency in couples with aneuploid offspring. Considering the frequency of aneuploidy among first trimester spontaneous abortions, we suggest that there may be a sub-population of persons predisposed to non-disjunction among couples with reproductive wastage.
منابع مشابه
An estrogen receptor genetic polymorphism and the risk of primary and secondary recurrent spontaneous abortion.
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عنوان ژورنال:
- Journal of medical genetics
دوره 22 1 شماره
صفحات -
تاریخ انتشار 1985